Derrek Lee led off the bottom of the 12th inning with a home run to give the Baltimore Orioles a 5-4 victory over the Cincinnati Reds on Friday night.
Lee sent a 1-2 pitch from Jose Arredondo (0-3) into the seats in left field to end the marathon. It was Lee's fifth home run, the first since May 8.
Cincinnati missed a chance to take the lead in the top of the 12th when Joey Votto was thrown out at the plate trying to score from first on a two-out double by Jay Bruce.
Mike Gonzalez (1-1) worked the 12th for the Orioles, who led 4-0 after four innings. Baltimore stranded 13 and went 2 for 14 with runners in scoring position.
The Orioles improved to 4-6 in extra-inning games.