CINCINNATI, OH (FOX19) - A new study by the University of Cincinnati found that a nasal spray containing an ingredient derived from hot chili peppers may help people clear up certain types of sinus inflammation.
The study was led by allergy researcher Jonathan Bernstein and appears in the August 2011 edition of Annals of Allergy, Asthma & Immunology.
The study compares the use of the Capsicum annum nasal spray to a placebo nasal spray in 44 subjects with a significant component of nonallergic rhinitis (i.e., nasal congestion, sinus pain, sinus pressure) for a period of two weeks.
Capsicum annum contains capsaicin, which is the main component of chili peppers and produces a hot sensation. Capsaicin is also the active ingredient in several topical medications used for temporary pain relief. It is approved for use by the U.S. Food and Drug Administration and is available over the counter.
"Basically, we concluded that the spray was safe and effective on non-allergic rhinitis," Bernstein says of the study which showed that participants who used a nasal spray with Capsicum reported a faster onset of action or relief, on average within a minute of using the spray, than the control group.
This is the first controlled trial where capsaicin was able to be used on a continuous basis to control symptoms. It is considered a significant advance, "because we don't really have good therapies for non-allergic rhinitis," says Bernstein, adding that in previous trials the ingredient was too hot to administer without anesthesia.
The study was funded by Dynova Laboratories. Bernstein, a professor in the division of immunology, allergy and rheumatology, at the UC College of Medicine, is a paid consultant for Dynova.