Philadelphia took the top spot this year, taking it from New York city, which held it for two years.
Cincinnati ranked second on the listed, followed by New York, Chicago, Detroit, Washington, D.C., Columbus, Ohio, San Francisco, Denver and New Haven, Conn.
The list was created by compiling data from the 300 Terminix branches across the country. The company created the ranking by evaluating service calls from customers, as well as confirmed cases by service professionals.
Ohio continues to be a hotbed of activity, with three of its cities making the top 15. Cleveland ranked 15th.
"Bedbugs continue to increase their presence across the U.S.," said Stoy Hedges, an entomologist with Terminix. "While major metropolitan areas are most at risk, it is important to note that bedbugs have been spotted in cities and towns across the country."
As travelers prepare to hit the road this summer, Terminix offers tips to slow the spread of bedbugs:
Check hotel headboards, mattresses and box springs for bedbugs and dark blood spots.
Hang all clothing. Leave nothing lying on the bed or furniture.
Avoid storing your clothing in the hotel's furniture drawers.
Store suitcases on a luggage rack as far from the bed as possible.
Vacuum suitcases when returning home, and immediately wash clothing in hot water.
Between trips, store luggage in a sealed plastic bag in a garage or basement, away from bedrooms.
If you suspect your hotel has bedbugs, ask for a change of rooms.
Bedbugs should only be treated by a trained pest control professional.
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