More than 14,000 people were in attendance at Trump's campaign stop at the Greater Columbus Convention Center Monday night.
He last publicly appeared in the perennial battleground state this summer during the GOP's first presidential debate in Cleveland.
Trump brought his campaign to the home state of one of his rivals for the GOP nomination - Ohio Gov. John Kasich.
Trump warmed up the massive crowd with an "OH-IO" chant before taking a shot at Ohio Governor John Kasich and their current polling positions. Kasich, a Republican, is also running for President.
"I'm 32. Kasich is, oh, should I mention it? Three. I heard he was dropping out. Somehow, you know, when you're the governor of a state, you've got to run that state," Trump said when comparing polling numbers.
Trump has polled well lately. He's at, or near, the top of most polls.
Kasich and Trump clashed on immigration during last week's Republican presidential debate in Milwaukee and again on a variety of issues in a tirade of barbs on Twitter.
"We are going to make America great again," Trump said to the crowd on hand.
The thousands were clad in Trump gear with the slogan, "Make America great again," while clutching and waving campaign signs.
It was Trump's plan for keeping lists of Syrian refugees that drew an audible protest from two people in the crowd, who were removed from the event.
"You can get them the hell out. Go ahead. Get out," Trump said.
The billionaire businessman outlined plans to defeat ISIS, strengthen the military, give back to veterans and dump the Obamacare system while stumping for more than an hour in the Buckeye State capital.
"We're going to win on trade. We're going to win on healthcare. We're going to win with the military," Trump touted.
Trump also outlined plans to support waterboarding.
"Would I approve waterboarding? You bet your ass I'd approve it," Trump told his supporters.
He also stirred up the crowd with his plan to build a wall to secure the nation's borders. At one point, he led the crowd in a chant of, "Build a wall! Build a wall!"
"We'll have a door in it. I'll tell you what, I want people to come into the country and so do you, but they have to come in legally," he said.
Trump spent an hour at the podium and left a promise with the sold-out crowd.
"The American Dream is dead. But, we're going to make it bigger and better and stronger than ever before," he said.
The latest polls show Trump remains in the lead for the Republican nomination.
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