ST. LOUIS, MO (FOX19) - March Madness is set to take over the Tri-State as local teams begin tournament play Friday.
Number 2-seed Xavier University faces off against 15-seed Weber State at the Scottrade Center in St. Louis at 9:20 p.m.
The Musketeers are at their best in the school's history.
Number 9-seed University of Cincinnati's Bearcats plays 8-seed Saint Joseph's Hawks in Spokane, Washington. The game starts at 9:57 p.m.
It's the first game for the Bearcats since losing a four-overtime game to UConn in the American Athletic Conference quarterfinals.
UC ranks among the top teams in the nation in defense. They'll rely on forward Gary Clark, who said he is fully recovered from an ankle injury.
This game will be UC's sixth straight NCAA Tournament appearance.