In Amelia, the 6800 block of Ohio 125 is shut down after trees and debris blew into the road, blocking it, about 3:50 a.m., Union Township dispatchers said.
In Leesburg, a vacant house was reported destroyed in the 11000 block of Cope Road, according to Highland County dispatchers. There also are reports of trees and barns down on U.S. 62 and State Route 771.
Earlier, northbound Interstate 75 flooded and closed for about an hour between westbound I-74 and Mitchell Avenue, Cincinnati police said.
Crews responded to reports of vehicles forced to pull off the highway due to high water just before 2:30 a.m. One vehicle was reported trapped in a middle lane.
High water also flooded dozens of basements across Hamilton County and in Cincinnati, dispatchers said.
Residents in Fairfax called 911 about 2:45 a.m. to report they were forced to evacuate homes on Simpson Avenue.
One report included a woman trapped on her porch due to high water.
LOOK: Debris from the Little Duck Creek in Fairfax left up on top of the bridge that passes over it. Roads muddy in the area. Watch @FOX19pic.twitter.com/uMkE669WZ1