A three-alarm fire broke out just before 3 AM at 4 West 15th Street in Over The Rhine.
Cincinnati Fire Companies were dispatched to a report of clothes on fire in the hallway of the building.
Firefighters reported heavy fire on the first and second floors of the structure, and that occupants were trapped in the building.
Cincinnati firefighters rescued a total of 34 individuals, using ground and aerial ladders, fire escapes and the stairwell after the fire had been extinguished on the various floors of the structure.
The fire cause is undetermined; the fire damage estimate is $100,000.
One firefighter suffered a minor injury while fighting the fire. Firefighter Christopher Cotter a 13-year veteran received six stitches as a result of a minor head laceration.